Cortical Anaplastic Ependymoma with Significant Desmoplasia: A Case Report and Literature Review
Ectopic brain anaplastic ependymomas with no connection to the ventricles are rare. We present a rare case of a 25-year-old male who presented with generalized convulsions. Computed tomography (CT), Magnetic Resonance Imaging (MRI), and magnetic resonance spectroscopy (MRS) showed characters of an i...
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Wiley
2013-01-01
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Series: | Case Reports in Oncological Medicine |
Online Access: | http://dx.doi.org/10.1155/2013/354873 |
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author | Alaa Eldin Elsharkawy Raid Abuamona Markus Bergmann Shadi Salem Evariste Gafumbegete Ernst Röttger |
author_facet | Alaa Eldin Elsharkawy Raid Abuamona Markus Bergmann Shadi Salem Evariste Gafumbegete Ernst Röttger |
author_sort | Alaa Eldin Elsharkawy |
collection | DOAJ |
description | Ectopic brain anaplastic ependymomas with no connection to the ventricles are rare. We present a rare case of a 25-year-old male who presented with generalized convulsions. Computed tomography (CT), Magnetic Resonance Imaging (MRI), and magnetic resonance spectroscopy (MRS) showed characters of an intra- and extra-axial lesion. Intraoperatively, the lesion was a cortical solid mass that had no connections to the dura or to the ventricle. The histological diagnosis showed an anaplastic ependymoma with WHO grade III with distinctive desmoplasia. A literature review of ectopic anaplastic ependymomas regarding their clinical presentations, management, and prognostic factors was performed. There is a need to establish a clinically based histopathological grading system for anaplastic ependymomas. Ectopic anaplastic ependymomas should be included in the preoperative differential diagnosis. |
format | Article |
id | doaj-art-b885beb29b684295a38bfc0b2c5557ad |
institution | Kabale University |
issn | 2090-6706 2090-6714 |
language | English |
publishDate | 2013-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Oncological Medicine |
spelling | doaj-art-b885beb29b684295a38bfc0b2c5557ad2025-02-03T01:21:39ZengWileyCase Reports in Oncological Medicine2090-67062090-67142013-01-01201310.1155/2013/354873354873Cortical Anaplastic Ependymoma with Significant Desmoplasia: A Case Report and Literature ReviewAlaa Eldin Elsharkawy0Raid Abuamona1Markus Bergmann2Shadi Salem3Evariste Gafumbegete4Ernst Röttger5Neurosurgical Department, Ludmillenstift Hospital, Ludmillenstraße 4-6, 49716 Meppen, GermanyNeurosurgical Department, Ludmillenstift Hospital, Ludmillenstraße 4-6, 49716 Meppen, GermanyDepartment of Clinical Neuropathology, Bremen, GermanyNeurosurgical Department, Ludmillenstift Hospital, Ludmillenstraße 4-6, 49716 Meppen, GermanyPathological Department, Ludmillenstift Hospital, Meppen, GermanyNeurosurgical Department, Ludmillenstift Hospital, Ludmillenstraße 4-6, 49716 Meppen, GermanyEctopic brain anaplastic ependymomas with no connection to the ventricles are rare. We present a rare case of a 25-year-old male who presented with generalized convulsions. Computed tomography (CT), Magnetic Resonance Imaging (MRI), and magnetic resonance spectroscopy (MRS) showed characters of an intra- and extra-axial lesion. Intraoperatively, the lesion was a cortical solid mass that had no connections to the dura or to the ventricle. The histological diagnosis showed an anaplastic ependymoma with WHO grade III with distinctive desmoplasia. A literature review of ectopic anaplastic ependymomas regarding their clinical presentations, management, and prognostic factors was performed. There is a need to establish a clinically based histopathological grading system for anaplastic ependymomas. Ectopic anaplastic ependymomas should be included in the preoperative differential diagnosis.http://dx.doi.org/10.1155/2013/354873 |
spellingShingle | Alaa Eldin Elsharkawy Raid Abuamona Markus Bergmann Shadi Salem Evariste Gafumbegete Ernst Röttger Cortical Anaplastic Ependymoma with Significant Desmoplasia: A Case Report and Literature Review Case Reports in Oncological Medicine |
title | Cortical Anaplastic Ependymoma with Significant Desmoplasia: A Case Report and Literature Review |
title_full | Cortical Anaplastic Ependymoma with Significant Desmoplasia: A Case Report and Literature Review |
title_fullStr | Cortical Anaplastic Ependymoma with Significant Desmoplasia: A Case Report and Literature Review |
title_full_unstemmed | Cortical Anaplastic Ependymoma with Significant Desmoplasia: A Case Report and Literature Review |
title_short | Cortical Anaplastic Ependymoma with Significant Desmoplasia: A Case Report and Literature Review |
title_sort | cortical anaplastic ependymoma with significant desmoplasia a case report and literature review |
url | http://dx.doi.org/10.1155/2013/354873 |
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