G‐Protein‐Coupled Receptor 84 Aggravates Early Brain Injury via Microglial NLRP3‐ASC Inflammasome After Subarachnoid Hemorrhage

G‐Protein‐Coupled Receptor 84 Aggravates Early Brain Injury via Microglial NLRP3‐ASC Inflammasome After Subarachnoid Hemorrhage

ABSTRACT Background Subarachnoid hemorrhage (SAH) is one of the most devastating hemorrhagic strokes. SAH causes neuroinflammation and leads to both early brain injury and delayed brain injury. G‐protein‐coupled receptor 84 (GPR84), one of the orphan class‐A G protein‐coupled receptors (GPCRs), exer...

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Main Authors: Kun Jiang, Yan Zou, Yue Song, Long'jiang Zhou, Bing'tao Zhang, Xiao'ming Zhou, Xin Zhang
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Brain and Behavior
Subjects:
G‐protein‐coupled receptor 84
NLRP3 inflammasome
pyroptosis
subarachnoid hemorrhage
Online Access:https://doi.org/10.1002/brb3.70379
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https://doi.org/10.1002/brb3.70379

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