Dynamics of cell-free tumor DNA correlate with early MRI response during chemoradiotherapy in rectal cancer

Dynamics of cell-free tumor DNA correlate with early MRI response during chemoradiotherapy in rectal cancer

Abstract Background In locally advanced rectal cancer, the prediction of tumor response during and after neoadjuvant treatment remains challenging. In terms of organ preservation, adaptive radiotherapy, and intensified (total) neoadjuvant therapies, biomarkers are desirable for patient stratificatio...

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Main Authors: Kerstin Clasen, Cihan Gani, Leon Schuetz, Stephan Clasen, Nadja Ballin, Irina Bonzheim, Michael Orth, Stephan Ossowski, Olaf Riess, Maximilian Niyazi, Christopher Schroeder, Olga Kelemen
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Radiation Oncology
Subjects:
ctDNA
cfDNA
NGS
Biomarker
Adaptive radiotherapy
Imaging
Online Access:https://doi.org/10.1186/s13014-024-02540-4
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https://doi.org/10.1186/s13014-024-02540-4

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