Beta vulgaris L. beetroot protects against iron-induced liver injury by restoring antioxidant pathways and regulating cellular functions

Beta vulgaris L. beetroot protects against iron-induced liver injury by restoring antioxidant pathways and regulating cellular functions

Abstract Beta vulgaris L. is a root vegetable that is consumed mainly as a food additive. This study aimed to describe the protective effect of B. vulgaris on Fe2+-mediated oxidative liver damage through in vitro, ex vivo, and in silico studies to establish a strong rationale for its protective effe...

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Main Authors: Oluwafemi Adeleke Ojo, Temiloluwa Rhoda Adeyemo, Matthew Iyobhebhe, Moses Dele Adams, Rotdelmwa Maimako Asaleye, Ikponmwosa Owen Evbuomwan, Jadesola Abdurrahman, Tobiloba Christiana Maduakolam-Aniobi, Charles Obiora Nwonuma, Olalekan Elijah Odesanmi, Adebola Busola Ojo
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:Scientific Reports
Subjects:
B. Vulgaris
Hepatic injury
Oxidative stress
Purinergic activity
Gluconeogenesis
Molecular simulation
Online Access:https://doi.org/10.1038/s41598-024-77503-6
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https://doi.org/10.1038/s41598-024-77503-6

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