Tolerability, safety and feasibility of metformin combined with chemoradiotherapy in patients with locally advanced cervical cancer: A phase II, randomized study
Background and purpose: Locally advanced cervical cancer is treated with chemoradiotherapy. The treatment-related morbidity is high. Tumor hypoxia has prognostic impact and represents a valid, interventional target. This phase II study investigated efficacy of the antidiabetic drug metformin to modi...
Saved in:
| Main Authors: | Kjersti Skipar, Tord Hompland, Kjersti V. Lund, Christina S. Fjeldbo, Kristina Lindemann, Taran P. Hellebust, Heidi Lyng, Kjersti Bruheim |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Medical Journals Sweden
2025-03-01
|
| Series: | Acta Oncologica |
| Subjects: | |
| Online Access: | https://medicaljournalssweden.se/actaoncologica/article/view/43045 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Establishment of a chemoresistant laryngeal cancer cell model to study chemoresistance and chemosensitization responses via transcriptomic analysis and a tumor‐on‐a‐chip platform
by: Christian R. Moya‐Garcia, et al.
Published: (2025-05-01) -
Antihypoxic Activities of Methanolic Extract of Silybum marianum and Silymarin in Asphyctic, Haemic, and Circulatory Hypoxia Models in Mice
by: Mohammad Eghbali, et al.
Published: (2025-03-01) -
Peculiarities of expression of HIF-1Α and HIF-3Α in hypothalamus of Wistar rats under the influence of intermittent hypobaric hypoxia
by: A. V. Abramov, et al.
Published: (2017-08-01) -
Hypoxia
by: P. F. Litvitsky
Published: (2016-02-01) -
Hipoksi ve Kanser
by: Sümeyye Aydogan Türkoğlu, et al.
Published: (2021-09-01)