Tolerability, safety and feasibility of metformin combined with chemoradiotherapy in patients with locally advanced cervical cancer: A phase II, randomized study

Tolerability, safety and feasibility of metformin combined with chemoradiotherapy in patients with locally advanced cervical cancer: A phase II, randomized study

Background and purpose: Locally advanced cervical cancer is treated with chemoradiotherapy. The treatment-related morbidity is high. Tumor hypoxia has prognostic impact and represents a valid, interventional target. This phase II study investigated efficacy of the antidiabetic drug metformin to modi...

Full description

Saved in:
Bibliographic Details
Main Authors: Kjersti Skipar, Tord Hompland, Kjersti V. Lund, Christina S. Fjeldbo, Kristina Lindemann, Taran P. Hellebust, Heidi Lyng, Kjersti Bruheim
Format: Article
Language:English
Published: Medical Journals Sweden 2025-03-01
Series:Acta Oncologica
Subjects:
cervical cancer
multimodal imaging
hypoxia biomarkers
hypoxia modification
metformin
randomized phase II trial
Online Access:https://medicaljournalssweden.se/actaoncologica/article/view/43045
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://medicaljournalssweden.se/actaoncologica/article/view/43045

Similar Items