Genetically supported causal genes for rheumatoid arthritis: Mendelian randomization and co‐localization analyses

Genetically supported causal genes for rheumatoid arthritis: Mendelian randomization and co‐localization analyses

Abstract Background Rheumatoid arthritis (RA) is a globally prevalent condition that has a significant impact on morbidity and mortality rates. As a result, there is growing interest in understanding its pathogenetic mechanisms, particularly genetic susceptibility. To explore the potential genes tha...

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Main Authors: Yuanyuan Niu, Fan Su, Simin Chen, Jingnan Wang, Shuoyang Zhang, Ruiru Li, Yu Kuang, Liuqin Liang, Youjun Xiao, Hanshi Xu
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:Rheumatology & Autoimmunity
Subjects:
causal genes
expression quantitative trait loci
inflammation
Mendelian randomization
rheumatoid arthritis
Online Access:https://doi.org/10.1002/rai2.12145
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https://doi.org/10.1002/rai2.12145

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