The single-cell spatial landscape of stage III colorectal cancers

The single-cell spatial landscape of stage III colorectal cancers

Abstract We conducted a spatial analysis of stage III colorectal adenocarcinomas using Hyperion Imaging Mass Cytometry, examining 52 tumors to assess the tumor microenvironment at the single-cell level. This approach identified 10 distinct cell phenotypes in the tumor microenvironment, including str...

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Main Authors: Andrew Su, HoJoon Lee, Minh Tran, Richard C. dela Cruz, Anuja Sathe, Xiangqi Bai, Ignacio Wichmann, Lance Pflieger, Bryce Moulton, Tyler Barker, Derrick Haslem, David Jones, Lincoln Nadauld, Quan Nguyen, Hanlee P. Ji, Terence Rhodes
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-025-00853-5
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https://doi.org/10.1038/s41698-025-00853-5

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