Noise-augmented directional clustering of genetic association data identifies distinct mechanisms underlying obesity.
Clustering genetic variants based on their associations with different traits can provide insight into their underlying biological mechanisms. Existing clustering approaches typically group variants based on the similarity of their association estimates for various traits. We present a new procedure...
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Main Authors: | Andrew J Grant, Dipender Gill, Paul D W Kirk, Stephen Burgess |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2022-01-01
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Series: | PLoS Genetics |
Online Access: | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1009975&type=printable |
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