BTLA agonist attenuates Th17-driven inflammation in a mouse model of steroid-resistant asthma

BTLA agonist attenuates Th17-driven inflammation in a mouse model of steroid-resistant asthma

IntroductionSteroid-resistant asthma does not respond adequately to corticosteroid treatment. The underlying mechanisms driving corticosteroid resistance remain poorly understood, partly due to the absence of suitable animal models. Identifying the immunomodulatory pathways and mechanisms driving st...

Full description

Saved in:
Bibliographic Details
Main Authors: Christine Quach, Xin Li, Pedram Shafiei-Jahani, Meng Li, Stephen Shen, Doumet Georges Helou, Benjamin P. Hurrell, Pejman Soroosh, Omid Akbari
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Immunology
Subjects:
steroid-resistant asthma
neutrophilic asthma
BTLA
HVEM
Th17
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1552394/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2025.1552394/full

Similar Items