Evaluation of Adjunctive Aminoglycoside Therapy Compared to β-Lactam Monotherapy in Critically Ill Patients with Gram-Negative Bloodstream Infections

Evaluation of Adjunctive Aminoglycoside Therapy Compared to β-Lactam Monotherapy in Critically Ill Patients with Gram-Negative Bloodstream Infections

<b>Background/Objectives</b>: Gram-negative bloodstream infections (GN-BSIs) in the critically ill carry significant mortality, which is exacerbated by delays in appropriate therapy. To improve the time to effective therapy, aminoglycosides are often recommended as empiric adjunctive ant...

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Bibliographic Details
Main Authors: Joshua Eudy, Aaron M. Chase, Divisha Sharma, Zoheb Irshad Sulaiman, August Anderson, Ashley Huggett, Lucy Gloe, Daniel T. Anderson
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Antibiotics
Subjects:
bloodstream infection
intensive care
aminoglycoside
antimicrobial stewardship
Online Access:https://www.mdpi.com/2079-6382/14/5/497
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