Myt1l haploinsufficiency leads to obesity and multifaceted behavioral alterations in mice

Myt1l haploinsufficiency leads to obesity and multifaceted behavioral alterations in mice

Abstract Background The zinc finger domain containing transcription factor Myt1l is tightly associated with neuronal identity and is the only transcription factor known that is both neuron-specific and expressed in all neuronal subtypes. We identified Myt1l as a powerful reprogramming factor that, i...

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Bibliographic Details
Main Authors: Markus Wöhr, Wendy M. Fong, Justyna A. Janas, Moritz Mall, Christian Thome, Madhuri Vangipuram, Lingjun Meng, Thomas C. Südhof, Marius Wernig
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Molecular Autism
Subjects:
Transcription factor
Autism
Obesity
Social behavior
Ultrasonic vocalization
Online Access:https://doi.org/10.1186/s13229-022-00497-3
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https://doi.org/10.1186/s13229-022-00497-3

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