Polyfunctionality and breadth of HIV-1 antibodies are associated with delayed disease progression.

Polyfunctionality and breadth of HIV-1 antibodies are associated with delayed disease progression.

HIV-1 infection leads to chronic disease requiring life-long treatment and therefore alternative therapeutics, a cure and/or a protective vaccine are needed. Antibody-mediated effector functions could have a role in the fight against HIV-1. However, the properties underlying the potential beneficial...

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Main Authors: Marloes Grobben, Margreet Bakker, Angela I Schriek, Liesbeth J J Levels, Jeffrey C Umotoy, Khadija Tejjani, Mariëlle J van Breemen, Ryan N Lin, Steven W de Taeye, Gabriel Ozorowski, Neeltje A Kootstra, Andrew B Ward, Stephen J Kent, P Mark Hogarth, Bruce D Wines, Rogier W Sanders, Amy W Chung, Marit J van Gils
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-12-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1012739
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https://doi.org/10.1371/journal.ppat.1012739

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