Imaging of human stem cell-derived dopamine grafts correlates with behavioural recovery and reveals microstructural brain changes

Imaging of human stem cell-derived dopamine grafts correlates with behavioural recovery and reveals microstructural brain changes

Cell therapy is a promising therapeutic intervention for Parkinson's disease (PD) and is currently undergoing safety and efficacy testing in clinical trials worldwide. The goals of this project were (1) to determine whether [18F]Fluorodopa or [18F]Fallypride imaging correlates robustly with fun...

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Main Authors: Stephen J. Paisey, Lucy R. Jones, David J. Harrison, Nicola J. Drummond, Olivia Z. Edwards, Maurice A. Canham, Victoria H. Roberton, Christopher Marshall, Greg Parker, Rachel Hills, Anne E. Rosser, Emma L. Lane, Stephen B. Dunnett, Tilo Kunath, Yaniv Assaf, Mariah J. Lelos
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Neurobiology of Disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996125001263
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