Granzyme K+CD8+ T cells interact with fibroblasts to promote neutrophilic inflammation in nasal polyps

Granzyme K+CD8+ T cells interact with fibroblasts to promote neutrophilic inflammation in nasal polyps

Abstract Sophisticated interactions between stromal and immune cells play crucial roles in various biological and pathological processes. In chronic rhinosinusitis with nasal polyps (CRSwNP), the upper airway inflammation in many patients is driven by TH2, ILC2, and eosinophils, thus being treated w...

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Main Authors: Cui-Lian Guo, Chong-Shu Wang, Zhi-Chao Wang, Fei-Fan Liu, Lin Liu, Yang Yang, Xia Li, Bei Guo, Ruo-Yu Lu, Bo Liao, Jin-Xin Liu, Hai Wang, Jia Song, Yin Yao, Li-Ping Zhu, Di Yu, Zheng Liu
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-54685-1
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https://doi.org/10.1038/s41467-024-54685-1

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