Genetically Predicted Frailty Index Is Associated With Increased Risk of Multiple Metabolic Diseases: 175 226 European Participants in a Mendelian Randomization Study

Genetically Predicted Frailty Index Is Associated With Increased Risk of Multiple Metabolic Diseases: 175 226 European Participants in a Mendelian Randomization Study

ABSTRACT Background A relationship between frailty index (FI) and metabolic diseases (MDs) has been reported in previous observational studies. However, the causality between them remains unclear. This study aimed to examine the causal effect of FI on MDs. Methods We performed a bidirectional two‐sa...

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Bibliographic Details
Main Authors: Hexing Wang, Haifeng Zhang, Dongliang Tang, Yinshuang Yao, Junlan Qiu, Xiaochen Shu
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Journal of Diabetes
Subjects:
frailty index
mendelian randomization
metabolic diseases
Online Access:https://doi.org/10.1111/1753-0407.70062
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