The T cell-mediated tumor killing patterns revealed tumor heterogeneous and proposed treatment recommendation in ovary cancer

The T cell-mediated tumor killing patterns revealed tumor heterogeneous and proposed treatment recommendation in ovary cancer

Abstract Background Immune checkpoint inhibitors (ICIs) have greatly improved cancer treatment, but the role of genes related to T cell-mediated tumor killing (TTK) sensitivity in ovarian cancer (OV) is unclear. Methods This study analyzed 1367 OV patients and 11 independent cohorts. The unsupervise...

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Bibliographic Details
Main Authors: Xinglin Wen, Beining Yin, Li Lin, Long Liu, Siyuan Weng, Hui Xu, Yuyuan Zhang, Jinhai Deng, Ruiying Liao, Cungeng Fan
Format: Article
Language:English
Published: Springer 2024-12-01
Series:Discover Oncology
Subjects:
Ovary cancer
T cell-mediated tumor killing
Immune microenvironment
Somatic mutation analysis
Metabolism analysis
Cancer treatment
Online Access:https://doi.org/10.1007/s12672-024-01635-4
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https://doi.org/10.1007/s12672-024-01635-4

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