Macrophages in the premetastatic and metastatic niche: key functions and therapeutic directions

Abstract Metastasis plays a significant role in the high mortality rates associated with cancer and is usually the endpoint of a series of sequential and dynamic events. A crucial step in metastasis development and progression is the formation of a premetastatic niche (PMN), which provides a conduci...

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Bibliographic Details
Main Authors: Yana Qi, Dongmei Sun, Xiaoyang Zhai, Feihu Chen, Jiling Niu, Hui Zhu
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-025-06556-6
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