Brain organoid models for studying the function of iPSC-derived microglia in neurodegeneration and brain tumours

Brain organoid models for studying the function of iPSC-derived microglia in neurodegeneration and brain tumours

Microglia represent the main resident immune cells of the brain. The interplay between microglia and other cells in the central nervous system, such as neurons or other glial cells, influences the function and ability of microglia to respond to various stimuli. These cellular communications, when di...

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Bibliographic Details
Main Authors: Angelica Maria Sabogal-Guaqueta, Teresa Mitchell-Garcia, Jasmijn Hunneman, Daniëlle Voshart, Arun Thiruvalluvan, Floris Foijer, Frank Kruyt, Marina Trombetta-Lima, Bart J.L. Eggen, Erik Boddeke, Lara Barazzuol, Amalia M. Dolga
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Neurobiology of Disease
Subjects:
Microglia
Organoids
iPSC
Neurodegenerative diseases
Glioblastoma
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996124003449
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