Analysis of glutamate content in food and dietary exposure assessment to glutamate among the Chinese population

Monosodium glutamate (MSG), a flavor-enhancing substance, was re-evaluated by the European Food Safety Authority (EFSA) in 2017, which established an acceptable daily intake (ADI) of 0–30 mg/kg bw/day. Despite this, comprehensive risk assessment data remain limited, particularly in China, a major pr...

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Main Authors: Weining Tian, Ling yong, Hongjian Miao, Xingfen Yang, Qinzhi Wei, Sheng Wei, Haixia Sui, Xiao Xiao, Jianwen Li, Huali Wang, Shanyawen Li, Jiongjiong Chang, Tong Ou, Weichunbai Zhang, Yan Song, Zhaoping Liu
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Applied Food Research
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Online Access:http://www.sciencedirect.com/science/article/pii/S277250222500246X
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author Weining Tian
Ling yong
Hongjian Miao
Xingfen Yang
Qinzhi Wei
Sheng Wei
Haixia Sui
Xiao Xiao
Jianwen Li
Huali Wang
Shanyawen Li
Jiongjiong Chang
Tong Ou
Weichunbai Zhang
Yan Song
Zhaoping Liu
author_facet Weining Tian
Ling yong
Hongjian Miao
Xingfen Yang
Qinzhi Wei
Sheng Wei
Haixia Sui
Xiao Xiao
Jianwen Li
Huali Wang
Shanyawen Li
Jiongjiong Chang
Tong Ou
Weichunbai Zhang
Yan Song
Zhaoping Liu
author_sort Weining Tian
collection DOAJ
description Monosodium glutamate (MSG), a flavor-enhancing substance, was re-evaluated by the European Food Safety Authority (EFSA) in 2017, which established an acceptable daily intake (ADI) of 0–30 mg/kg bw/day. Despite this, comprehensive risk assessment data remain limited, particularly in China, a major producer and consumer of MSG. This study analyzed glutamate content in natural and MSG-containing foods in China and assessed dietary exposure using a simple distribution model. A group ADI of 0–120 mg/kg bw/day (as glutamic acid) was established. Results showed that China's general population consumes 20.2 mg/kg bw/day of glutamates, equivalent to 16.8 % of the group ADI, with the 95th percentile (P95) intake at 67.3 mg/kg mg/kg bw/day (56.1 % of the ADI). Children aged 3–6 years exhibited the highest intake, with P95 reaching 97.2 % of the group ADI. These findings provide essential data for risk assessment and regulatory decisions on glutamate consumption in China, underscoring the need to monitor dietary exposure for public health safety.
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series Applied Food Research
spelling doaj-art-b784224ddc2f4d5e90cc066f6560dc2f2025-08-20T03:31:20ZengElsevierApplied Food Research2772-50222025-06-015110093810.1016/j.afres.2025.100938Analysis of glutamate content in food and dietary exposure assessment to glutamate among the Chinese populationWeining Tian0Ling yong1Hongjian Miao2Xingfen Yang3Qinzhi Wei4Sheng Wei5Haixia Sui6Xiao Xiao7Jianwen Li8Huali Wang9Shanyawen Li10Jiongjiong Chang11Tong Ou12Weichunbai Zhang13Yan Song14Zhaoping Liu15Key Laboratory of Food Safety Risk Assessment, National Health Commission of the People’s Republic of China, China National Center for Food Safety Risk Assessment, Beijing 100022, China; National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 102206, ChinaKey Laboratory of Food Safety Risk Assessment, National Health Commission of the People’s Republic of China, China National Center for Food Safety Risk Assessment, Beijing 100022, ChinaKey Laboratory of Food Safety Risk Assessment, National Health Commission of the People’s Republic of China, China National Center for Food Safety Risk Assessment, Beijing 100022, ChinaSouthern Medical University, Guangzhou 510515, ChinaSouthern Medical University, Guangzhou 510515, ChinaSouthern University of Science and Technology, Shenzhen 518055, ChinaKey Laboratory of Food Safety Risk Assessment, National Health Commission of the People’s Republic of China, China National Center for Food Safety Risk Assessment, Beijing 100022, ChinaKey Laboratory of Food Safety Risk Assessment, National Health Commission of the People’s Republic of China, China National Center for Food Safety Risk Assessment, Beijing 100022, ChinaKey Laboratory of Food Safety Risk Assessment, National Health Commission of the People’s Republic of China, China National Center for Food Safety Risk Assessment, Beijing 100022, ChinaKey Laboratory of Food Safety Risk Assessment, National Health Commission of the People’s Republic of China, China National Center for Food Safety Risk Assessment, Beijing 100022, ChinaYantai Center for Disease Control and Prevention, Yantai 264003, ChinaYantai Center for Disease Control and Prevention, Yantai 264003, ChinaKey Laboratory of Food Safety Risk Assessment, National Health Commission of the People’s Republic of China, China National Center for Food Safety Risk Assessment, Beijing 100022, ChinaKey Laboratory of Food Safety Risk Assessment, National Health Commission of the People’s Republic of China, China National Center for Food Safety Risk Assessment, Beijing 100022, ChinaKey Laboratory of Food Safety Risk Assessment, National Health Commission of the People’s Republic of China, China National Center for Food Safety Risk Assessment, Beijing 100022, China; Corresponding authors at: China National Center for Food Safety Risk Assessment, 37 Guangqu Road Building 2, Beijing 100022, China.Key Laboratory of Food Safety Risk Assessment, National Health Commission of the People’s Republic of China, China National Center for Food Safety Risk Assessment, Beijing 100022, China; Corresponding authors at: China National Center for Food Safety Risk Assessment, 37 Guangqu Road Building 2, Beijing 100022, China.Monosodium glutamate (MSG), a flavor-enhancing substance, was re-evaluated by the European Food Safety Authority (EFSA) in 2017, which established an acceptable daily intake (ADI) of 0–30 mg/kg bw/day. Despite this, comprehensive risk assessment data remain limited, particularly in China, a major producer and consumer of MSG. This study analyzed glutamate content in natural and MSG-containing foods in China and assessed dietary exposure using a simple distribution model. A group ADI of 0–120 mg/kg bw/day (as glutamic acid) was established. Results showed that China's general population consumes 20.2 mg/kg bw/day of glutamates, equivalent to 16.8 % of the group ADI, with the 95th percentile (P95) intake at 67.3 mg/kg mg/kg bw/day (56.1 % of the ADI). Children aged 3–6 years exhibited the highest intake, with P95 reaching 97.2 % of the group ADI. These findings provide essential data for risk assessment and regulatory decisions on glutamate consumption in China, underscoring the need to monitor dietary exposure for public health safety.http://www.sciencedirect.com/science/article/pii/S277250222500246XMonosodium glutamate (MSG)Dietary glutamate exposureFood safety assessmentChinese populationFood additive regulationAmino acid intake
spellingShingle Weining Tian
Ling yong
Hongjian Miao
Xingfen Yang
Qinzhi Wei
Sheng Wei
Haixia Sui
Xiao Xiao
Jianwen Li
Huali Wang
Shanyawen Li
Jiongjiong Chang
Tong Ou
Weichunbai Zhang
Yan Song
Zhaoping Liu
Analysis of glutamate content in food and dietary exposure assessment to glutamate among the Chinese population
Applied Food Research
Monosodium glutamate (MSG)
Dietary glutamate exposure
Food safety assessment
Chinese population
Food additive regulation
Amino acid intake
title Analysis of glutamate content in food and dietary exposure assessment to glutamate among the Chinese population
title_full Analysis of glutamate content in food and dietary exposure assessment to glutamate among the Chinese population
title_fullStr Analysis of glutamate content in food and dietary exposure assessment to glutamate among the Chinese population
title_full_unstemmed Analysis of glutamate content in food and dietary exposure assessment to glutamate among the Chinese population
title_short Analysis of glutamate content in food and dietary exposure assessment to glutamate among the Chinese population
title_sort analysis of glutamate content in food and dietary exposure assessment to glutamate among the chinese population
topic Monosodium glutamate (MSG)
Dietary glutamate exposure
Food safety assessment
Chinese population
Food additive regulation
Amino acid intake
url http://www.sciencedirect.com/science/article/pii/S277250222500246X
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