Oral-gut axis in inflammation: periodontitis exacerbates ulcerative colitis via microbial dysbiosis and barrier disruption

Oral-gut axis in inflammation: periodontitis exacerbates ulcerative colitis via microbial dysbiosis and barrier disruption

Abstract Background Periodontitis is a chronic inflammatory disease, having significant impact on systemic conditions. Ulcerative colitis (UC) is a chronic relapsing inflammatory disorder of the intestines. Studies have suggested a potential association between periodontitis and UC. This study aims...

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Bibliographic Details
Main Authors: Jinping Yu, Jinglu Lyu, Tongxin Zhu, Yang Li, Hanping Xia, Qing Liu, Lili Li, Bin Chen
Format: Article
Language:English
Published: BMC 2025-06-01
Series:BMC Oral Health
Subjects:
Periodontitis
Ulcerative colitis
Dextran sodium sulfate
Immune response
Gut microbiota
Intestinal barrier
Online Access:https://doi.org/10.1186/s12903-025-06269-8
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https://doi.org/10.1186/s12903-025-06269-8

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