The relationship of methylation and mRNA expression profile of AUTS2 with suicidal ideation in adolescents with bipolar depression

The relationship of methylation and mRNA expression profile of AUTS2 with suicidal ideation in adolescents with bipolar depression

Abstract Objective This study aims to explore the correlation between the methylation levels of the AUTS2 gene and suicidal ideation in adolescents with bipolar depression, and investigate the mediating effect of AUTS2 mRNA expression levels. Methods A total of 73 adolescents diagnosed with bipolar...

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Bibliographic Details
Main Authors: Xiaoqin Shen, Chengji Wang, Alimire Alimujiang, Cheng Zhang, Shaohong Zou, Lu Liu
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Psychiatry
Subjects:
Adolescent bipolar depression
Suicidal ideation
AUTS2 gene
DNA methylation
mRNA expression levels
Online Access:https://doi.org/10.1186/s12888-025-06927-9
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https://doi.org/10.1186/s12888-025-06927-9

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