The Signaling Pathway of PGE2 and Its Regulatory Role in T Cell Differentiation

Prostaglandin E2 (PGE2) is a lipid mediator derived from the fatty acid arachidonic acid. As an essential inflammatory factor, PGE2 has a critical impact on immune regulation through the prostanoid E (EP) receptor pathway. T cells, including CD4+ and CD8+ T cell subsets, play crucial roles in the ad...

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Bibliographic Details
Main Authors: Yang An, Jiameng Yao, Xiaoyin Niu
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2021/9087816
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