Modal-nexus auto-encoder for multi-modality cellular data integration and imputation
Abstract Heterogeneous feature spaces and technical noise hinder the cellular data integration and imputation. The high cost of obtaining matched data across modalities further restricts analysis. Thus, there’s a critical need for deep learning approaches to effectively integrate and impute unpaired...
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| Main Authors: | Zhenchao Tang, Guanxing Chen, Shouzhi Chen, Jianhua Yao, Linlin You, Calvin Yu-Chian Chen |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2024-10-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-024-53355-6 |
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