The Deubiquitinase OTUD1 Influences HIV-1 Release by Regulating the Host Restriction Factor BST-2

The Deubiquitinase OTUD1 Influences HIV-1 Release by Regulating the Host Restriction Factor BST-2

Bone marrow stromal cell antigen 2 (BST-2) is a restriction factor for human immunodeficiency virus type I (HIV-1) and plays an important role in regulating the release of viral particles. However, the antiviral efficacy of BST-2 is antagonized by the HIV-1-encoded accessory protein Vpu, which facil...

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Bibliographic Details
Main Authors: Man-Di Zhang, Fan Chen, Wen-Qiang He, Ying Lu, Feng-Liang Liu, Hong-Guang Zhang, Liu-Meng Yang, Chun-Sheng Dong, Si-Dong Xiong, Yong-Tang Zheng
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Viruses
Subjects:
deubiquitinase
OTUD1
BST-2
HIV-1
Online Access:https://www.mdpi.com/1999-4915/17/2/260
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