Formulation of pH responsive polymeric hydrogels for prolonged delivery of famciclovir with biosafety evaluation

Formulation of pH responsive polymeric hydrogels for prolonged delivery of famciclovir with biosafety evaluation

Abstract Recent study aimed to fabricate pH responsive, intelligent, Pluronic F127 based polymeric system for controlled delivery of Famciclovir. Nine formulations were developed through free radical polymerization. Polymeric system exhibited pH dependent swelling by showing higher degree of swellin...

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Main Authors: Irum Iftikhar, Kashif Barkat, Syed Faisal Badshah, Muhammad Umer Ashraf, Yasir Mehmood, Irfan Anjum, Gamal A. Shazly, Amira Metouekel, Youssouf Ali Younous, Mohammed Bourhia
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Pluronic F127
Famciclovir
Polymeric system
Reduced dosing frequency
Prolonged release
Online Access:https://doi.org/10.1038/s41598-025-96739-4
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https://doi.org/10.1038/s41598-025-96739-4

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