Brd4 is essential for IL-1β-induced inflammation in human airway epithelial cells.

<h4>Background</h4>Chronic inflammation and oxidative stress are key features of chronic obstructive pulmonary disease (COPD). Oxidative stress enhances COPD inflammation under the control of the pro-inflammatory redox-sensitive transcription factor nuclear factor-kappaB (NF-κB). Histone...

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Bibliographic Details
Main Authors: Younis M Khan, Paul Kirkham, Peter J Barnes, Ian M Adcock
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0095051
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