Generalized linear modeling of flow cytometry data to analyze immune responses in tuberculosis vaccine research

Abstract Tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) kills ~1.3 million people annually. Accordingly, vaccines and sophisticated analytical tools are necessary to evaluate their effectiveness. To address these challenges, we created a Generalized Linear Model (GLM) framework to eval...

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Bibliographic Details
Main Authors: Pablo Maldonado, Taru S. Dutt, Amanda Hitpas, Brendan Podell, G. Brooke Anderson, Marcela Henao-Tamayo
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:npj Systems Biology and Applications
Online Access:https://doi.org/10.1038/s41540-025-00572-4
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