Deep5mC: Predicting 5-methylcytosine (5mC) methylation status using a deep learning transformer approach

DNA methylations, such as 5-methylcytosine (5mC), are crucial in biological processes, and aberrant methylations are strongly linked to various human diseases. Genomic 5mC is not randomly distributed but exhibits a strong association with genomic sequences. Thus, various computational methods were d...

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Bibliographic Details
Main Authors: Evan Kinnear, Houssemeddine Derbel, Zhongming Zhao, Qian Liu
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Computational and Structural Biotechnology Journal
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Online Access:http://www.sciencedirect.com/science/article/pii/S2001037025000340
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