Identification and validation of CDK1 as a promising therapeutic target for Eriocitrin in colorectal cancer: a combined bioinformatics and experimental approach

Identification and validation of CDK1 as a promising therapeutic target for Eriocitrin in colorectal cancer: a combined bioinformatics and experimental approach

Abstract Background Colorectal cancer (CRC) is a prevalent malignancy worldwide, associated with significant morbidity and mortality. Cyclin-dependent kinase 1 (CDK1) plays a crucial role in cell cycle regulation and has been implicated in various cancers. This study aimed to evaluate the prognostic...

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Bibliographic Details
Main Authors: Jiemiao Shen, Xing Gong, Haili Ren, Xia Tang, Hairong Yu, Yilu Tang, Shen Chen, Minghui Ji
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Cancer
Subjects:
Colorectal cancer
Cyclin-dependent kinase 1
Prognosis
Molecular docking
Eriocitrin
Online Access:https://doi.org/10.1186/s12885-025-13448-x
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