Chronic Wound Initiation: Single-Cell RNAseq of Cutaneous Wound Tissue and Contributions of Oxidative Stress to Initiation of Chronicity

Chronic Wound Initiation: Single-Cell RNAseq of Cutaneous Wound Tissue and Contributions of Oxidative Stress to Initiation of Chronicity

Chronic wounds (CWs) in humans affect millions of people in the US alone, cost billions of dollars, cause much suffering, and still there are no effective treatments. Patients seek medical care when wound chronicity is already established, making it impossible to investigate factors that initiate ch...

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Bibliographic Details
Main Authors: Parnian Jabbari, Jane H. Kim, Brandon H. Le, Wei Zhang, Huimin Zhang, Manuela Martins-Green
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Antioxidants
Subjects:
healing
cellular heterogeneity
wound microenvironment
oxidative stress
diabetic foot ulcers
animal models
Online Access:https://www.mdpi.com/2076-3921/14/2/214
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