Herstellung diastereomerenreiner l- oder u-konfigurierter 1-hydroxybenzylierter Tetrahydroisochinolin-Vorläufer für Aporphin-, Protoberberin-, Quettamin- und Phthalid-Alkaloide (Stereoselektive Synthese von (±)-Ushinsunin und (±)-Oliverolin)
6,7-Dialkoxy-1-bromomagnesio-2-pivaloyl-tetrahydroisoquinolines (THIQ), prepared as previously described for the unsubstituted reagent, are added to bromo-, methoxy-, and ethoxycarbonyl-substituted benzaldehydes to give 1-hydroxybenzylated THIQs of u-configuration exclusively (2a-4a, 5). These are...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | deu |
| Published: |
Swiss Chemical Society
1985-08-01
|
| Series: | CHIMIA |
| Online Access: | https://www.chimia.ch/chimia/article/view/9676 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|