3D printing of biological tooth with multiple ordered hierarchical structures
Natural teeth fulfill functional demands by their heterogeneity. The composition and hydroxyapatite (HAp) nanostructured orientation of enamel differ from those of dentin. However, mimicking analogous materials still exhibit a significant challenge. Herein, a bottom-up, sequential approach was formu...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-02-01
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| Series: | Materials Today Bio |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590006425000122 |
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| author | Menglu Zhao Yanan Geng Suna Fan Xiang Yao Jiexin Wang Meifang Zhu Yaopeng Zhang |
| author_facet | Menglu Zhao Yanan Geng Suna Fan Xiang Yao Jiexin Wang Meifang Zhu Yaopeng Zhang |
| author_sort | Menglu Zhao |
| collection | DOAJ |
| description | Natural teeth fulfill functional demands by their heterogeneity. The composition and hydroxyapatite (HAp) nanostructured orientation of enamel differ from those of dentin. However, mimicking analogous materials still exhibit a significant challenge. Herein, a bottom-up, sequential approach was formulated by combining shear-induced and magnetic-assisted 3D printing technology, enabling the fabrication of the intricate microstructure of a multi-material dental crown, where the HAp nanostructure is highly ordered and almost perpendicular to each other at the dentinoenamel junction (DEJ). The HAp nanorods were first induced to achieve high orientation in each printed line, then formed a plane with a vertical structure of DEJ under the shear force and magnetic field at dentin and enamel, respectively, and finally 3D-printed into a dental crown with bilayered parts exhibiting site-specific composition, texture, and outstanding biocompatibility. This novel approach can be applied to design and fabricate natural tooth crowns, indicating the potential for multi-level and multi-dimensional texture control. |
| format | Article |
| id | doaj-art-b691746dee914dae89c4d544267b34ac |
| institution | Kabale University |
| issn | 2590-0064 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Materials Today Bio |
| spelling | doaj-art-b691746dee914dae89c4d544267b34ac2025-01-17T04:52:16ZengElsevierMaterials Today Bio2590-00642025-02-01301014543D printing of biological tooth with multiple ordered hierarchical structuresMenglu Zhao0Yanan Geng1Suna Fan2Xiang Yao3Jiexin Wang4Meifang Zhu5Yaopeng Zhang6State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai, 201620, PR ChinaState Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai, 201620, PR ChinaState Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai, 201620, PR ChinaState Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai, 201620, PR ChinaState Key Laboratory of Organic-Inorganic Composites, Beijing University of Chemical Technology, Beijing, 100029, PR ChinaState Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai, 201620, PR China; Corresponding author.zmf@dhu.edu.cnState Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai, 201620, PR China; Corresponding author.Natural teeth fulfill functional demands by their heterogeneity. The composition and hydroxyapatite (HAp) nanostructured orientation of enamel differ from those of dentin. However, mimicking analogous materials still exhibit a significant challenge. Herein, a bottom-up, sequential approach was formulated by combining shear-induced and magnetic-assisted 3D printing technology, enabling the fabrication of the intricate microstructure of a multi-material dental crown, where the HAp nanostructure is highly ordered and almost perpendicular to each other at the dentinoenamel junction (DEJ). The HAp nanorods were first induced to achieve high orientation in each printed line, then formed a plane with a vertical structure of DEJ under the shear force and magnetic field at dentin and enamel, respectively, and finally 3D-printed into a dental crown with bilayered parts exhibiting site-specific composition, texture, and outstanding biocompatibility. This novel approach can be applied to design and fabricate natural tooth crowns, indicating the potential for multi-level and multi-dimensional texture control.http://www.sciencedirect.com/science/article/pii/S2590006425000122Magnetic-assisted 3D printingHydroxyapatiteAnisotropy architectureMechanical propertiesBionic crown |
| spellingShingle | Menglu Zhao Yanan Geng Suna Fan Xiang Yao Jiexin Wang Meifang Zhu Yaopeng Zhang 3D printing of biological tooth with multiple ordered hierarchical structures Materials Today Bio Magnetic-assisted 3D printing Hydroxyapatite Anisotropy architecture Mechanical properties Bionic crown |
| title | 3D printing of biological tooth with multiple ordered hierarchical structures |
| title_full | 3D printing of biological tooth with multiple ordered hierarchical structures |
| title_fullStr | 3D printing of biological tooth with multiple ordered hierarchical structures |
| title_full_unstemmed | 3D printing of biological tooth with multiple ordered hierarchical structures |
| title_short | 3D printing of biological tooth with multiple ordered hierarchical structures |
| title_sort | 3d printing of biological tooth with multiple ordered hierarchical structures |
| topic | Magnetic-assisted 3D printing Hydroxyapatite Anisotropy architecture Mechanical properties Bionic crown |
| url | http://www.sciencedirect.com/science/article/pii/S2590006425000122 |
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