Lithium and neuroprotection: a review of molecular targets and biological effects at subtherapeutic concentrations in preclinical models of Alzheimer’s disease

Abstract Background Experimental studies consistently demonstrate that lithium modulates multiple intracellular signaling pathways involved in crucial neurobiological responses, highlighting its therapeutic potential in degenerative diseases. Lithium has demonstrated significant neuroprotective pote...

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Bibliographic Details
Main Authors: Vanessa de Jesus R. De-Paula, Marcia Radanovic, Orestes Vicente Forlenza
Format: Article
Language:English
Published: SpringerOpen 2025-05-01
Series:International Journal of Bipolar Disorders
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Online Access:https://doi.org/10.1186/s40345-025-00386-7
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