Characterization of Extracellular Vesicles Derived From Human Precision‐Cut Liver Slices in Metabolic Dysfunction‐Associated Steatotic Liver Disease

Characterization of Extracellular Vesicles Derived From Human Precision‐Cut Liver Slices in Metabolic Dysfunction‐Associated Steatotic Liver Disease

ABSTRACT Extracellular vesicles (EVs) are cell‐produced, membrane‐surrounded vesicles that harbour the biological features of donor cells. In the current study, we are the first to isolate and characterize EVs isolated from human precision‐cut liver slices (PCLS), obtained from both healthy and meta...

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Main Authors: Yana Geng, Ke Luo, Janine Stam, Dorenda Oosterhuis, Alan R. Gorter, Marius vanden Heuvel, Rossella Crescitelli, Vincent E. deMeijer, Justina C. Wolters, Peter Olinga
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:Journal of Extracellular Biology
Subjects:
biomarker
hepatic fibrosis
human precision‐cut liver slices
metabolic dysfunction‐associated steatohepatitis
proteomics
Online Access:https://doi.org/10.1002/jex2.70043
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https://doi.org/10.1002/jex2.70043

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