Adenovirus mediated gene delivery of α-calcitonin gene-related peptide facilitates osseointegration of implant in ovariectomized rat

Adenovirus mediated gene delivery of α-calcitonin gene-related peptide facilitates osseointegration of implant in ovariectomized rat

Background: Osteoporosis, which adversely affected osseointegration of dental implants, became prevalent with the entry of ageing era. Recent studies indicated that α-calcitonin gene-related peptide (α-CGRP) played a role in modulating osteoporosis. However, due to the plasma half-life of α-CGRP bei...

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Bibliographic Details
Main Authors: Yin Guozhu, Wu yihua, You Zhu, Dai li, Zhang Tianqi, Li Jia, Zhang Shizhou
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Regenerative Therapy
Subjects:
α-CGRP
Adenovirus
Osseointegration
Implant
Gene therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2352320425000525
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