Efficacy and prognostic analysis of venetoclax combined with hypomethylating agents for induction therapy in acute myeloid leukemia: a multi-center real-world study on indication-specific stratification, molecular markers, and hematologic toxicities

Efficacy and prognostic analysis of venetoclax combined with hypomethylating agents for induction therapy in acute myeloid leukemia: a multi-center real-world study on indication-specific stratification, molecular markers, and hematologic toxicities

Abstract The combination of venetoclax and hypomethylating agents (VEN + HMAs) has shown significant progress in treating acute myeloid leukemia (AML), especially for patients not suitable for intensive chemotherapy. However, outcomes for relapsed/refractory AML remain uncertain, and factors influen...

Full description

Saved in:
Bibliographic Details
Main Authors: Leiming Xia, Mengni Qu, Ling Ge, Yingying Chen, Beibei Zhou, Ting Shi, Yang Liu, Min Ruan, Liang Xia, Jian Hong, Jianjun Li, Wei Qian, Yu Zhang, Lei Jiang, Yiming Zhao, Wanlu Tian, Zhenqi Huang, Fengbo Jin, Jian Ge, Mingzhen Yang, Qingshu Zeng
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Cancer Cell International
Subjects:
Venetoclax
Hypomethylating agents
Acute myeloid leukemia
Induction therapy
Efficacy
Hematologic toxicities
Online Access:https://doi.org/10.1186/s12935-025-03858-z
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1186/s12935-025-03858-z

Similar Items