Near-infrared long lifetime upconversion nanoparticles for ultrasensitive microRNA detection via time-gated luminescence resonance energy transfer

Abstract Upconversion nanoparticle (UCNP)-based luminescence resonance energy transfer (LRET) biosensing offers advantages such as wash-free detection and precise biomolecule quantification. However, its sensitivity remains limited due to continuous energy transfer in co-doped UCNPs during LRET. Her...

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Main Authors: Suyeon Kim, Yeonkyung Park, Jiwoo Han, Hansol Kim, Hyowon Jang, Sohyung Kim, Dongkyu Kang, Min-Young Lee, Byeong-Ho Jeong, Yuree Byun, Eun-Kyung Lim, Juyeon Jung, Taejoon Kang, Joonseok Lee
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-62802-x
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