Impact of a Heterozygous C1R<sup>R301P/WT</sup> Mutation on Collagen Metabolism and Inflammatory Response in Human Gingival Fibroblasts

Periodontal Ehlers–Danlos syndrome arising from heterozygous pathogenic mutation in <i>C1R</i> and/or <i>C1S</i> genes is an autosomal-dominant disorder characterized by early-onset periodontitis. Due to the difficulties in obtaining and culturing the patient-derived gingival...

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Bibliographic Details
Main Authors: Chengjuan Qu, Cecilia Koskinen Holm
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/14/7/479
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