The Flavonoids and Monoterpenes from <i>Citrus unshiu</i> Peel Contained in Ninjinyoeito Synergistically Activate Orexin 1 Receptor: A Possible Mechanism of the Orexigenic Effects of Ninjinyoeito

Cancer cachexia, often observed in patients with advanced-stage cancer, is characterized by the loss of body weight and appetite. The Japanese herbal medicine Ninjinyoeito (NYT), which is composed of 12 crude herbal components, has been used as a therapeutic in Japan to improve anorexia and fatigue,...

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Main Authors: Kaori Ohshima, Kanako Miyano, Miki Nonaka, Sayaka Aiso, Mao Fukuda, Saho Furuya, Hideaki Fujii, Yasuhito Uezono
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Biomolecules
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Online Access:https://www.mdpi.com/2218-273X/15/4/533
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