HER2 expression in different cell lines at different inoculation sites assessed by [52Mn]Mn-DOTAGA(anhydride)-trastuzumab

PurposePositron emission tomography (PET) hybrid imaging targeting HER2 requires antibodies labelled with longer half-life isotopes. With a suitable radiation profile, 52Mn coupled with DOTAGA as a bifunctional chelator is a potential candidate. In this study, we investigated the tumor HER2 specific...

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Main Authors: Toàn Minh Ngô, Adrienn Vágner, Gábor Nagy, Gábor Ország, Tamás Nagy, Zoltán Szoboszlai, Csaba Csikos, Balázs Váradi, György Trencsényi, Gyula Tircsó, Ildikó Garai
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Pathology and Oncology Research
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Online Access:https://www.por-journal.com/articles/10.3389/pore.2025.1611999/full
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