Cancer‑associated fibroblasts: a pivotal regulator of tumor microenvironment in the context of radiotherapy

Cancer‑associated fibroblasts: a pivotal regulator of tumor microenvironment in the context of radiotherapy

Abstract Background In the course of tumor treatment, radiation therapy (RT) not only kills cancer cells, but also induces complex biological effects in non-malignant cells around cancer cells. These biological effects such as angiogenesis, changes in stromal composition and immune cell infiltration...

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Bibliographic Details
Main Authors: Linhui Zheng, Wenqi Cai, Yuan Ke, Xiaoyan Hu, Chunqian Yang, Runze Zhang, Huachao Wu, Dong Liu, Haijun Yu, Chaoyan Wu
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Cell Communication and Signaling
Subjects:
Cancer associated fibroblast
Radiation therapy
Tumor microenvironment
Immune microenvironment
Online Access:https://doi.org/10.1186/s12964-025-02138-7
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https://doi.org/10.1186/s12964-025-02138-7

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