Functional and Structural Alterations in Pediatric Multiple Sclerosis: A Systematic Review and a Preliminary Activation Likelihood Estimation Functional Magnetic Resonance Imaging Meta-Analysis

Functional and Structural Alterations in Pediatric Multiple Sclerosis: A Systematic Review and a Preliminary Activation Likelihood Estimation Functional Magnetic Resonance Imaging Meta-Analysis

Background/Objectives: Pediatric multiple sclerosis (MS) is a rare and complex neuroinflammatory disease characterized by demyelination and neurological dysfunction in individuals under 18 years of age. This systematic review and activation likelihood estimation (ALE) meta-analysis aimed to synthesi...

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Bibliographic Details
Main Authors: Nicoletta Cera, Joana Pinto, Ricardo Faustino
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Pediatric Reports
Subjects:
pediatric multiple sclerosis
functional MRI
structural brain alterations
activation likelihood estimation (ALE)
cognitive impairment
brain connectivity
Online Access:https://www.mdpi.com/2036-7503/17/3/57
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