B7 Homolog 4 (B7-H4)-Directed Agents in Oncology Clinical Trials: A Review

B7 homolog 4 (B7-H4) is a transmembrane protein found on immune cells and is frequently overexpressed in various solid tumors, making it a promising target for cancer therapy. B7-H4–directed agents, particularly antibody-drug conjugates (ADCs) like puxitatug samrotecan (AZD8205), felmetatug vedotin...

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Bibliographic Details
Main Authors: Meave Phipps, Gerald S. Falchook
Format: Article
Language:English
Published: Innovative Healthcare Institute 2025-04-01
Series:Journal of Immunotherapy and Precision Oncology
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Online Access:https://jipo.org/doi/pdf/10.36401/JIPO-24-34
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