Intratracheal Surfactant Administration Attenuates Hyperoxia-Induced Lung Injury and Fibrosis in Neonatal Rats

Intratracheal Surfactant Administration Attenuates Hyperoxia-Induced Lung Injury and Fibrosis in Neonatal Rats

Background: Hyperoxia decreases surfactant production and suggests exogenous surfactant may be a potential treatment for hyperoxia-induced lung injury. This study aimed to investigate the effects of an animal-derived surfactant on hyperoxia-induced lung injury and fibrosis in newborn rats. Meth...

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Bibliographic Details
Main Authors: Jiunn-Song Jiang, Chi-Chun Hsieh, Hsiu-Chu Chou, Chung-Ming Chen
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-10-01
Series:Pediatric Respirology and Critical Care Medicine
Subjects:
collagen; lung; newborn; transforming growth factor-β1; tumor necrosis factor-α
Online Access:https://journals.lww.com/prcm/fulltext/2024/08040/intratracheal_surfactant_administration_attenuates.3.aspx
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https://journals.lww.com/prcm/fulltext/2024/08040/intratracheal_surfactant_administration_attenuates.3.aspx

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