Assessing the Comorbidity Cycle Between Psoriasis and Addiction Based on ICD Coding in the Stockholm Psoriasis Cohort
The comorbidity cycle between psoriasis and addictions remains unclear. The study aimed to investigate the cumulative incidence of addictions in psoriasis patients and controls in the Stockholm Psoriasis Cohort (SPC). The SPC is an observational cohort study that enrolled psoriasis patients between...
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Medical Journals Sweden
2025-01-01
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| Series: | Acta Dermato-Venereologica |
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| Online Access: | https://medicaljournalssweden.se/actadv/article/view/41221 |
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| author | Hannah Wecker Axel Svedbom Fabio Sánchez Orrego Stefanie Ziehfreund Mona Ståhle Alexander Zink |
| author_facet | Hannah Wecker Axel Svedbom Fabio Sánchez Orrego Stefanie Ziehfreund Mona Ståhle Alexander Zink |
| author_sort | Hannah Wecker |
| collection | DOAJ |
| description | The comorbidity cycle between psoriasis and addictions remains unclear. The study aimed to investigate the cumulative incidence of addictions in psoriasis patients and controls in the Stockholm Psoriasis Cohort (SPC). The SPC is an observational cohort study that enrolled psoriasis patients between 2001 and 2005 and matched controls using the Swedish Total Population Register. Data were complemented by medical records from 1987–2013, focusing on 11 addiction diagnoses and the date of their assignment. Overall, 4,545 individuals (56.4% female; median age: 40) were included: 722 psoriasis patients and 3,823 controls. Patients showed 1.4 times (95% confidence interval: 0.98–1.98) higher odds of addiction diagnosis than controls. Alcohol dependency was the most common addiction diagnosis (78.2%), which was more frequent in patients than in controls (94.3% vs 73.6%, p = 0.009). Furthermore, patients showed 4.3 times (1.85–11.56) higher odds of receiving an addiction diagnosis after their initial psoriasis diagnosis than before. Results showed a tendency towards a higher risk of addiction in psoriasis patients, suggesting potential psoriasis-triggered addictive behaviour. Nevertheless, both substance abuse triggering psoriasis and chronic psoriasis inflammation triggering addictions have to be considered. In both cases, addictive behaviour needs to be addressed in psoriasis healthcare as a driver for poor disease outcome and comorbidities.
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| format | Article |
| id | doaj-art-b5f0604a6d5f40cbb585819191b9c692 |
| institution | Kabale University |
| issn | 0001-5555 1651-2057 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Medical Journals Sweden |
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| series | Acta Dermato-Venereologica |
| spelling | doaj-art-b5f0604a6d5f40cbb585819191b9c6922025-01-03T08:46:03ZengMedical Journals SwedenActa Dermato-Venereologica0001-55551651-20572025-01-0110510.2340/actadv.v105.41221Assessing the Comorbidity Cycle Between Psoriasis and Addiction Based on ICD Coding in the Stockholm Psoriasis CohortHannah Wecker0Axel Svedbom1Fabio Sánchez Orrego2Stefanie Ziehfreund3Mona Ståhle4Alexander Zink5Technical University of Munich, TUM School of Medicine and Health, Department of Dermatology and Allergy, Munich, GermanyDivision of Dermatology and Venereology, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Dermatology and Venereology Clinic, Karolinska University Hospital, Stockholm, SwedenDepartment of Clinical Neuroscience, Karolinska Institute and Metadonsektionen, Beroendecentrum Stockholm, Stockholm, SwedenTechnical University of Munich, TUM School of Medicine and Health, Department of Dermatology and Allergy, Munich, GermanyDivision of Dermatology and Venereology, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden Technical University of Munich, TUM School of Medicine and Health, Department of Dermatology and Allergy, Munich, Germany; Division of Dermatology and Venereology, Department of Medicine Solna, Karolinska Institutet, Stockholm, SwedenThe comorbidity cycle between psoriasis and addictions remains unclear. The study aimed to investigate the cumulative incidence of addictions in psoriasis patients and controls in the Stockholm Psoriasis Cohort (SPC). The SPC is an observational cohort study that enrolled psoriasis patients between 2001 and 2005 and matched controls using the Swedish Total Population Register. Data were complemented by medical records from 1987–2013, focusing on 11 addiction diagnoses and the date of their assignment. Overall, 4,545 individuals (56.4% female; median age: 40) were included: 722 psoriasis patients and 3,823 controls. Patients showed 1.4 times (95% confidence interval: 0.98–1.98) higher odds of addiction diagnosis than controls. Alcohol dependency was the most common addiction diagnosis (78.2%), which was more frequent in patients than in controls (94.3% vs 73.6%, p = 0.009). Furthermore, patients showed 4.3 times (1.85–11.56) higher odds of receiving an addiction diagnosis after their initial psoriasis diagnosis than before. Results showed a tendency towards a higher risk of addiction in psoriasis patients, suggesting potential psoriasis-triggered addictive behaviour. Nevertheless, both substance abuse triggering psoriasis and chronic psoriasis inflammation triggering addictions have to be considered. In both cases, addictive behaviour needs to be addressed in psoriasis healthcare as a driver for poor disease outcome and comorbidities. https://medicaljournalssweden.se/actadv/article/view/41221alcoholismaddictioncohort studiescomorbiditypsoriasissubstance abuse |
| spellingShingle | Hannah Wecker Axel Svedbom Fabio Sánchez Orrego Stefanie Ziehfreund Mona Ståhle Alexander Zink Assessing the Comorbidity Cycle Between Psoriasis and Addiction Based on ICD Coding in the Stockholm Psoriasis Cohort Acta Dermato-Venereologica alcoholism addiction cohort studies comorbidity psoriasis substance abuse |
| title | Assessing the Comorbidity Cycle Between Psoriasis and Addiction Based on ICD Coding in the Stockholm Psoriasis Cohort |
| title_full | Assessing the Comorbidity Cycle Between Psoriasis and Addiction Based on ICD Coding in the Stockholm Psoriasis Cohort |
| title_fullStr | Assessing the Comorbidity Cycle Between Psoriasis and Addiction Based on ICD Coding in the Stockholm Psoriasis Cohort |
| title_full_unstemmed | Assessing the Comorbidity Cycle Between Psoriasis and Addiction Based on ICD Coding in the Stockholm Psoriasis Cohort |
| title_short | Assessing the Comorbidity Cycle Between Psoriasis and Addiction Based on ICD Coding in the Stockholm Psoriasis Cohort |
| title_sort | assessing the comorbidity cycle between psoriasis and addiction based on icd coding in the stockholm psoriasis cohort |
| topic | alcoholism addiction cohort studies comorbidity psoriasis substance abuse |
| url | https://medicaljournalssweden.se/actadv/article/view/41221 |
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