PGRN as an emerging regulator of lipid metabolism in neurodegenerative diseases
Abstract Dysregulated lipid metabolism in microglia represents a hallmark of neuroinflammation and is often observed in a variety of neurodegenerative diseases. The exact molecular mechanisms underlying the induction of altered lipid homeostasis and how it contributes to neurodegeneration remain to...
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| Main Authors: | Yiyue Shi, Wenyu Hou, Bei Li, Caihong Zhu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-06-01
|
| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-025-08272-9 |
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