EV-microRNA signatures in pregnant women with idiopathic recurrent pregnancy loss: deciphering microRNAome pathway networks at feto-maternal interface

EV-microRNA signatures in pregnant women with idiopathic recurrent pregnancy loss: deciphering microRNAome pathway networks at feto-maternal interface

BackgroundDespite extensive research in the past decade, the exact pathogenesis of recurrent pregnancy loss (RPL) remains unknown. At the time of pregnancy, human placenta releases microRNAs (miRNAs) enclosed in extracellular vesicles (EVs), which enter into maternal circulation and play an importan...

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Bibliographic Details
Main Authors: Chitra Bhardwaj, Minakshi Rohilla, Seema Chopra, Anupriya Kaur, Inusha Panigrahi, Priyanka Srivastava
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
Subjects:
recurrent pregnancy loss
extracellular vesicles
miRNA
feto-maternal interface
biomarker
small RNA sequencing
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1578738/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1578738/full

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