Development of an Innovative Dual Construct for Targeted Drug Delivery in the Oral Cavity

Development of an Innovative Dual Construct for Targeted Drug Delivery in the Oral Cavity

<b>Background:</b> Oral lichen planus (OLP) is a chronic autoimmune disease of the oral mucosa, classified among potentially malignant oral disorders (OPMDs). It is characterized by keratinocyte apoptosis and persistent inflammation. Standard treatments involve topical corticosteroids ad...

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Main Authors: Elena Mazzinelli, Ilaria Favuzzi, Marianna Messina, Giorgia Fratocchi, Federica Vincenzoni, Eleonora Santo Stefano, Francesco Cecconi, Carlo Lajolo, Alessia Basco, Raffaella Castagnola, Massimo Cordaro, Francesco Scilla, Valerio Papa, Alessandro Arcovito, Ilaria Cacciotti, Giuseppina Nocca
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Pharmaceutics
Subjects:
poly(lactic acid) fibers
poly(lactic-<i>co</i>-glycolic acid) nanoparticles
chitosan coating
dexamethasone
mucoadhesivity
drug delivery
Online Access:https://www.mdpi.com/1999-4923/17/2/272
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