In situ tumor cell engineering reverses immune escape to enhance immunotherapy effect

In situ tumor cell engineering reverses immune escape to enhance immunotherapy effect

The underlying cause of low response rates to existing immunotherapies is that tumor cells dominate tumor immune escape through surface antigen deficiency and inducing tumor immunosuppressive microenvironment (TIME). Here, we proposed an in situ tumor cell engineering strategy to disrupt tumor immun...

Full description

Saved in:
Bibliographic Details
Main Authors: Shujun Liu, Shijun Yuan, Meichen Liu, Jinhu Liu, Shunli Fu, Tong Gao, Shuang Liang, Xinyan Huang, Xinke Zhang, Yongjun Liu, Zipeng Zhang, Na Zhang
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Tumor engineering
MHC-I
T cell recognition
CD55
ICOSL+ B cell
Immunotherapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383524003496
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

http://www.sciencedirect.com/science/article/pii/S2211383524003496

Similar Items